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Anti-bacterial and Anti-oxidant Studies on the Stem Bark Extracts o... |
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Prunusafricana belongs to the Rosaceae family. It is a |
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geographically wide spread tree to forest habitats of the |
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African continent. P. africana is one of the most popular |
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plants in traditional medicine for treating various |
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ailments. It is mainly used to treat benign prostate |
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hyperplasia (BHP). The study was aimed to evaluate the |
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anti-bacterial and anti-oxidant activities of stem bark |
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extract from P. africana. The air dried and powdered |
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plant material (300 g) was first soaked with 400mLofn- |
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hexane for 72 hours and yielded 1.5g of n-hexane extract. |
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Residue was soaked with 400mL of ethyl acetate for |
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48hours and afforded 4.5g of ethyl acetate extract. |
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Finally, residue was soaked with 400mLof methanol and |
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yielded 12.5g of methanol extract. The ethyl acetate |
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extract showed inhibition zones of 16mm and 11mm against |
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Escherichia coli and Staphylococcus aureus, |
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respectively.The extracts also showed encourage results |
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of DPPH radical scavenging activity at various |
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concentrations. The ethyl acetate extract of P. africana |
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of stem bark showed promising activity against E. coli, |
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ATCC24534 and S.aureus,ATCC26452. Anti-oxidant activities |
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also were shown prospective result, selectively at lowest |
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concentration and lowest absorbance. This means the |
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result of the study was confirmed that the lowest |
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concentration of 12.5mg/mL and absorbance of 0.208the |
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scavenging activity was 77.6%, while at the highest |
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concentration of 200mg/mL and absorbance of 0.288the |
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scavenging activity was 68.9%. |
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Date Published: 2020-07-14 10:20:01 |
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Identifier: ijmpd-2-may-june-2020 |
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Item Size: 5740329 |
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Language: English |
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Media Type: texts |
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# Topics |
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stem bark; medicine; ailments;anti-ba... |
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folkscanomy_academic |
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