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DTIC ADB225250: Iron Deprivations Treatment of Breast Cancer: Pre-C... |
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by Defense Technical Information Center |
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Progress has been made in the study of iron deprivation |
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as a potential treatment modality for breast cancer. |
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Enhanced macrophage activation with an augmented acute |
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phase response has been implicated as a source of |
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potential treatment related toxicity. Deferoxamine |
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appears to interact successfully with Doxorubicin in |
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vitro in inhibiting the growth of some breast cancer cell |
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lines. New, direct evidence for iron-deprivation inducing |
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apoptosis arose in a collaborative study and has been |
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submitted for publication. Sufficient monoclonal antibody |
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reagents are now on hand to begin in vivo anti-tumor |
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experiments with the MDA-MB-231 breast cancer cell line. |
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Date Published: 2018-02-26 22:14:42 |
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Identifier: DTIC_ADB225250 |
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Item Size: 29858735 |
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Language: english |
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Media Type: texts |
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# Topics |
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DTIC Archive; Kemp, John D ; IOWA UNI... |
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