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DTIC ADA451342: Antigens for a Vaccine That Prevents Severe Malaria |
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by Defense Technical Information Center |
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Malaria is the primary infectious disease threat facing |
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the U.S. solider, and is the leading cause of all |
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casualties during tropical deployments. The long-term |
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objective of this project is to identify and prepare the |
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malaria parasite forms causing severe anemia, and then |
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apply functional genomics and bioinformatics tools to |
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identify 15 to 30 proteins that could form the basis for |
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an effective vaccine at both the pre-erythrocytic and |
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blood stages of malaria infection. The project will then |
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evaluate these lead candidates for their recognition by |
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sera collected from immune individuals, in order to |
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identify the leading 3 to 5 candidates for a blood stage |
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vaccine that prevents severe malarial anemia. |
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Date Published: 2018-06-03 23:34:12 |
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Identifier: DTIC_ADA451342 |
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Item Size: 3020135 |
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Language: english |
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Media Type: texts |
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# Topics |
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DTIC Archive; Duffy, Patrick E ; SEAT... |
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