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DTIC ADA411445: An Improved Bio-Optical Method for Tumor Detection ...
by Defense Technical Information Center
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Optical approaches to breast cancer (BC) detection show
promise over conventional methods because they have
potential to work in the denser tissue of younger
patients and because they do not use ionizing radiation
which has been shown to induce cancer in some patients.
Three technologies will be combined in this effort. (a)
Optical probing, using controlled light at specific
wavelengths, is becoming a respected approach to cancer
tumor detection. A much-published RADAR-based method
known as frequency-domain photon migration (FDPM) gives
very high sensitivity. (b) Spectral fingerprint analysis
of fluorescence emission is the basis for cancer and
precancer classification affecting surface cells. This
has been shown for cervical and lung cancers. (c) Reading
images, such as x-ray films, allows the tumor to stand
out relative to the expected complex image of the breast.
An optical hardware system was envisioned and preliminary
testing performed. Hardware was to be based on using
technically similar systems used in unrelated industrial
applications to make hardware development affordable.
Specific systems were identified. Ultimately,
collaborators could not be found to modify their systems,
and system development proved to be prohibitively costly.
Discussions with other researchers has provided a voice
for this approach within the community, paving the way
for valuable contributions to BC detection.
Date Published: 2018-05-12 06:13:00
Identifier: DTIC_ADA411445
Item Size: 38958290
Language: english
Media Type: texts
# Topics
DTIC Archive; Leatham, James G ; APPL...
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