DTIC ADA165015: Urinary and Hematological Indices of Hypohydration, | |
by Defense Technical Information Center | |
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As part of a large scale field feeding system test we had | |
the unique opportunity to collect and study hundreds of | |
overnight urine aliquots which were obtained immediately | |
prior to a fasting blood sample on days 1, 20, and 44 of | |
the field test. To evaluate the hydrational status of | |
test subjects and criteria of hypohydration, urine | |
aliquots were categorized by specific gravity or = 1.03 | |
(n=124) or 1.03 (n=540). Creatinine levels were elevated | |
(p.001) in the concentrated urine samples, but a | |
decreased trend in Na(+)/K(+) ratios in these samples | |
failed to achieve statistical significance (p=0.1). | |
However, when individuals with high specific gravity | |
urine were further subclassified by a criterion of weight | |
loss 3% from original body weight, then creatinine | |
concentrations were elevated (p=.05) while Na(+)/K(+) | |
ratios were decreased (p=.05) when compared with levels | |
in subjects also with high specific gravity but weight | |
loss 3%. Serum urea nitrogen/creatinine ratios were | |
significantly increased (days 1 and 44, p=.02) in test | |
subjects whose urine samples exceeded 1.03 in specific | |
gravity. The results of this study indicated that | |
prodromal hypohydration, indicated by concomitant | |
elevations in urinary specific gravity and creatinine, | |
was not reflected in the common indices of circulatory | |
hypohydration- hematocrit and osmolality. Alternatively, | |
urea nitrogen/creatinine ratio may be a sensitive | |
circulatory index of imminent hypohydration. | |
Date Published: 2018-02-06 05:43:54 | |
Identifier: DTIC_ADA165015 | |
Item Size: 15208083 | |
Language: english | |
Media Type: texts | |
# Topics | |
DTIC Archive; Francesconi,R P ; ARMY... | |
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dticarchive | |
additional_collections | |
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@chris85 | |
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