The issue is in the math itself. Cause/effect is built-in. Start
  here. End there. There's ways WITHIN to mitigate somewhat, but
  the issue is systemic.

  Time won't likely be conquered until causation assumptions
  within mathematical cascades are allowed to be mitigated.

  Won't be easy: the overwhelming success of mathematics as a tool
  for physics discovery (and theoretical physics is dependent upon
  it nearly entirely now) means it's not likely other options will
  have much sway.

  Systems thinking comes closer, although not perfect either.
  Platonism is hard to remove. In short, there's a "doctor, heal
  thyself" problem in mathematics; the assumption of ideal
  realities separate from our own that are somehow capable of
  describing perfectly ... this.

  But what room is there for the day theoretical physicist had his
  coffee secretly switched to decaf and the latest political news
  got him really angry that morning, and it effected his primary
  hypothesis that led into a perfectly constructed something that
  works perfectly within its own realm, but neglects psychological
  state of the physicist in its generation in the first place?