Personally, I believe the human lifespan has a maximal cap of
around 120 years. I expect to get 84-88 years myself. Anything
beyond that will likely require biological implants, transplants
or stem cells.
Even if we can control the actions of the telemeres, I still
doubt more than 120 is possible without "something added" to us.
If we live to 250, 1000, 10,000 years? We'll adapt. There's ways
we haven't begun to consider, because we're NOT in that
situation having to face it. We'll have to think of solutions
for problems that we don't even imagine existing yet.