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Research Officer Job at Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia [1]

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Date: 2025-07

Posted 29 July, 2025

An excellent opportunity is available for a Research Officer to join the Structural Biology Division at Australia's pre-eminent biomedical research institute.



About the Position

The Glukhova lab is interested in understanding the structural mechanisms of Wnt signalling, with a particular focus on membrane protein complexes and the application of this knowledge for drug discovery. We are seeking a highly motivated postdoctoral scientist with expertise in mass spectrometry and proteomics, with a particular focus on crosslinking mass spectrometry. The postdoctoral scientist will be responsible for driving the project aimed at understanding the organisation of membrane signalling complexes in cells and following their isolation for structural characterisation. This position will join a multidisciplinary and highly collaborative environment in their effort to understand the molecular events underpinning signal initiation during Wnt signalling and how these processes are altered in colorectal and pancreatic cancers.



Selection Criteria

Essential Knowledge and Skills:

PhD or equivalent in mass spectrometry (MS) and laboratory experience

Ability to lead mass spectrometry-based projects with minimal oversight

Knowledge and hands-on experience in crosslinking mass spectrometry including in-cell and purified proteins

Working knowledge of MS instrumentation and operation, maintenance, and troubleshooting (Experience with Thermo Fisher Scientific Orbitrap machines including Eclipse and Astral is preferred)

Proficient in advanced statistical methods and design and analysis of MS experiments

Ability to analyse and troubleshoot difficult samples

Demonstrated ability and potential for excellence and productivity in research

Research experience that has resulted in publications, conference papers or reports

Desirable Knowledge and Skills:

Experience with expression and purification of membrane proteins

Experience working with different crosslinker types

MS-informed protein structure modelling

Mammalian and/or insect cell culture

Expertise in running Proteomics and Phosphoproteomics experiments

Personal Qualities:

Ability to drive a research project independently

Excellent communication skills and the ability to work constructively within a team environment

Excellent attention to detail, ensuring that data, new methods and theories are accurate, of high-quality and accessible to other researchers

Ability to manage time effectively and be reliable and approachable

Terms of Appointment

This is a full-time position available for two years. Salary is Academic Level A6-A8 $104,071-$111,707, depending on qualifications and experience. Up to 17% superannuation and very attractive salary packaging options are available.



General enquiries can be directed to Alisa Glukhova - [email protected]

A position description is available here.



How to Apply

Please apply by uploading your CV, cover letter and a document addressing the key selection criteria in pdf format.



Application Closing Date: 9 September 2025

WEHI - Brighter together

WEHI is where the world's brightest minds collaborate and innovate to make discoveries that will help us to live healthier for longer. Our medical researchers have been serving the community for more than 100 years. We bring together people with different skills and experience who are committed to long-term discovery. Our teams of researchers are committed to solving the most complex health problems, making transformative discoveries for cancer, infectious and immune diseases, developmental disorders and healthy ageing.

WEHI is a place where people are able to shine. People who are inquisitive, who are committed, who are passionate. People who want to make a difference. And we are committed to ensuring they have the tools to flourish, personally and professionally. We are a community of researchers, students and professional service staff who work towards achieving discoveries that improve human health. We are driven by collaboration, curiosity and creativity. We are committed to making a positive difference to the lives of people in Australia and around the world. We are WEHI. We are brighter together.

WEHI's commitment to diversity and inclusion

At WEHI we strive to foster a flexible working environment that encourages individual differences and promotes collaboration and creativity. We recognise that talent does not sit within a single identifiable group in our society and that WEHI's ability to shape contemporary scientific thinking and deliver leading professional services relies on a diversity of thought within our organisation. Our action to promote gender equality has been recognised with an Athena SWAN Bronze Award from Science in Australia Gender Equity (SAGE) and we offer a range of support for women researchers.

Our commitment to celebrating diversity and addressing inequities is further demonstrated through our Diversity and Inclusion Strategy, Gender Action Plan, Reconciliation Action Plan and our WE-Pride network for LGBTQIA+ staff and students. We actively encourage applications from, people with a disability, culturally, religiously and linguistically diverse people and people with diverse genders and sexualities. Should you require support during the recruitment process due to special needs or consideration, please contact the People and Culture team.

WEHI's commitment to Indigenous employment

WEHI is working to create a future where Aboriginal and Torres Strait Islander peoples will be engaged at the scientific frontier, making exciting discoveries and decisions about the future of health in this country, and part of a leading professional services workforce supporting the realisation of these discoveries. We are committed to creating a culturally safe workplace and offering career development and leadership opportunities to First Nations staff and students. We strongly encourage any Aboriginal and Torres Strait Islander peoples to apply.

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[1] Url: https://jobs.theconversation.com/jobs/420738682-research-officer-at-walter-and-eliza-hall-institute-of-medical-research

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