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"Markedly reduced" protection against rising BQ.1, BQ1.1, XBB, & XBB.1 COVID subvariants [1]

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Date: 2022-12-27

MEDSCAPE … Four [COVID-19] Omicron subvariants … will be the most common strains going from person to person this winter, new research predicts…. BQ.1, BQ1.1, XBB, and XBB.1 … [and they] are the most resistant to neutralizing antibodies, researcher Qian Wang, PhD, and colleagues report. This means you have no or "markedly reduced" protection against infection from [them], even if you've already had COVID-19 or are vaccinated and boosted multiple times, including with a bivalent vaccine. [And] all available monoclonal antibody treatments are mostly or completely ineffective against these subvariants.

.. The findings are definitely "worrisome," said Eric Topol, MD, founder and director of the Scripps Translational Research Institute in La Jolla, California, and editor-in-chief of Medscape [even with evidence from] Singapore and France [suggesting] that at least two of these variants [are less damaging than expected … — it appears that] COVID-19 vaccinations and prior infections can still reduce the risk for serious outcomes such as hospitalization and death, the researchers write [and the CDC concurs].

The "Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants" study was published online this week in the journal Cell….

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[1] Url: https://www.dailykos.com/stories/2022/12/27/2144119/--Markedly-reduced-protection-against-rising-BQ-1-BQ1-1-XBB-amp-XBB-1-COVID-subvariants

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