GENE-SERVER


           _A_d_d_r_e_s_s:
           Dr. Dan Davison
           BCHS-5500
           Dept. of Biochemical and Biophysical Sciences
           University of Houston
           4800 Calhoun, Houston, Tx, 77204-5500

           _E_m_a_i_l: [email protected] (Internet), DAVISON@UHOU (Bitnet)

           _P_h_o_n_e: (713) 749-2801 (Dr. Davison)


           _D_e_s_c_r_i_p_t_i_o_n

           The Gene-Server is a mail response facility that will return
           a specific GenBank (tm) entry requested via e-mail.

           Other Services:

           The server  now  distributes  Protein  Information  Resource
           (PIR, also known as NBRF) protein sequence database entries.

           Molecular biology software for Apple  Macintosh,  DOS,  Unix
           and VAX-VMS computers is also available from the server.

           A number of information files (the  R.  Roberts  Restriction
           Enzyme  database; sequence analysis reference, and such) are
           distributed.

           The Matrix of Biological Knowledge Archive-Server files  are
           now available only from this address.

           Electronic mail searching of the protein  sequence  database
           is  available;  you simply send a properly formatted protein
           "query" sequence to a specific address on the server and the
           search  will  be  performed  automatically  and  the results
           returned via electronic mail.


           _________________________
           The information in this section is provided  in  accor-
           dance  with the copyright notice appearing at the front
           of this guide.




           September 10, 1990          NNSC        Section 3.1,  Page 1








           _N_e_t_w_o_r_k _A_c_c_e_s_s

           The server can be accessed via e-mail on the Internet,  BIT-
           NET, and UUCP networks.  The addresses to use are:

                [email protected] (Internet)
                bchs.uh.edu!genbank-server (Usenet)
                gene-server%bchs.uh.edu@CUNYVM (BITNET)

           Please be aware that a mail response program is not  "smart"
           and  can only respond to a limited set of commands.  GenBank
           entries are available by name and accession number only.

           Your request can consist of one of the following:

                HELP
                SEND HELP
                SEND LOCUS genbank_locus_name
                SEND INDEX index_name
                SEND ACCESSION accession_number

           "HELP" will result in a small help  file  being  sent  back;
           everyone  should  request  the  help message.  The file will
           contain up-to-date information  about  the  server,  access,
           release  numbers,  and  policies.   The  help  message  also
           includes all index names, so "SEND INDEX" no  longer  works.
           "SEND  INDEX  index_name"  (where "index_name" is one of the
           index files listed in the HELP message)  will  work.   "SEND
           LOCUS   genbank_locus_name"   will  return  via  e-mail  the
           requested locus if it exists, and an  error  message  if  it
           does  not.   Use  the index file in the HELP message to find
           the name of the entry, or use the accession number.

           The server runs every half hour and  will  handle  only  one
           request  at  a  time.  If you want more than one entry, send
           separate requests.

           Note that large GenBank entries (Lambda,  EBV,  tobacco  and
           liverwort  chloroplasts)  may not make it through the thread
           of mailers.  UUCP mailers, in particular, silently enforce a
           limit  of  64,000 characters in a single mail message.  Note
           also that Usenet mail is very unreliable;  you  should  con-
           sult  the "pathalias" database to construct a mail path from
           your machine to bchs.uh.edu.  A local Unix mail  wizard  may
           be able to help.

           IMPORTANT NOTE: "[email protected]" is an  MX  record.
           If  you  have problems reaching that address, ask your local



           September 10, 1990          NNSC        Section 3.1,  Page 2








           system mail expert how to  handle  addresses  that  are  "MX
           records."   As  a _v_e_r_y last resort, send email to one of the
           addresses given above.

           _W_h_o _C_a_n _U_s_e _t_h_e _C_a_t_a_l_o_g

           Anyone can use the catalog.

           _M_i_s_c_e_l_l_a_n_e_o_u_s

           The current version of GenBank on the server is Release  64.
           The  server  is  updated  as often as possible given funding
           (none) and  disk  space  constraints.   The  server  may  be
           updated daily in the future.

           Information and software is  exchanged  regularly  with  the
           European  Molecular  Biology  Laboratory (EMBL) File Server,
           but the specific files, syntax, and information vary between
           the two servers.

           The server contains a simple response to someone asking  for
           too  many  loci  or  otherwise abusing the service: it stops
           working for them.

           Questions  can  be  sent  to  [email protected]  (Internet)  or
           DAVISON@UHOU(BITNET).   Requests  to  talk to a human rather
           than a mail response program  should  be  sent  to  archive-
           [email protected].    By   popular   demand,   archive-
           [email protected] also works.

           This service is provided  by  the  Institute  for  Molecular
           Biology,  the Department of Biochemical and Biophysical Sci-
           ences, the University of  Houston  Academic  Computing  Ser-
           vices,  and the Office of the Vice President for Information
           Technologies.

           The server is not funded or related in any  with  the  DHHS,
           PHS,  National  Institutes  of Health, or its contractors or
           subcontractors on the GenBank contract.  GenBank is a trade-
           mark  of  the US Department of Health and Human Services, US
           Public Health Service.










           September 10, 1990          NNSC        Section 3.1,  Page 3