BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? Yes
Drug class: Antibiotic
USES
Treatment of infections susceptible to chlorampehnicol.
DOSAGE AND USAGE INFORMATION
How to take:
Tablet or capsule--Swallow with liquid.
Eye solution or ointment, ear solution or cream--Follow
label instructions.
When to take:
Tablet or capsule--1 hour before or 2 hours after
eating.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If
more than 2 hours, wait for next scheduled dose (don't
double this dose).
What drug does:
Prevents bacteria from growing and reproducing. Will
not kill viruses.
Time lapse before drug works:
2 to 5 days, depending on type and severity of
infection.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
Symptoms What To Do
Life-threatening:
Hives, rash Seek emergency treatment
intense itching, immediately.
faintness soon
after a dose
(anaphylaxis).
Common:
None expected
Infrequent:
Swollen face or Discontinue. Call doctor
extremities; diarrhea; right away.
nausea; vomiting;
numbness, tingling,
burning pain or
weakness in hands
and feet.
Headache, confusion Continue. Call doctor
when convenient.
Rare:
Pain, blurred vision, Discontinue. Call doctor
possible vision loss, right away.
sore throat, fever,
jaundice, anemia.
OVERDOSE
Symptoms:
Nausea, vomiting, diarrhea.
What to do:
Overdose unlikely to threaten life. If person takes
much larger amount than prescribed, call doctor,
poison-control center or hospital emergency room for
instructions.
WARNINGS AND PRECAUTIONS
Don't take if:
You are allergic to chloramphenicol.
It is prescribed for a minor disorder such as flu, cold
or mild sore throat.
Before you start, consult your doctor:
If you have had a blood disorder or bone-marrow disease.
If you have had kidney or liver disease.
If you have diabetes.
Over age 60:
Adverse reactions and side effects may be more frequent
and severe than in younger persons, particularly skin
irritation around rectum.
Pregnancy:
Risk ot unborn child outweighs drug benefits. Don't
use.
Breast-feeding:
Drug passes into milk. Avoid drug or discontinue
nursing until you finish medicine. Consult doctor for
advice on maintaining milk supply.
Infants and children:
Don't give to infants younger than 2.
Prolonged use:
You may become more susceptible to infections caused by
germs not responsive to chloramphenicol.
Skin and sunlight:
No problems expected.
Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how
medicine affects you. Don't work around dangerous
machinery. Don't climb ladders or work in high places.
Danger increases if you drink alcohol or take medicine
affecting alertness and reflexes.
Discontinuing:
Don't discontinue without doctor's advice until you
complete prescribed dose, even though symptoms diminish
or disappear.
Others:
Chloramphenicol can cause serious anemia. Frequent
laboratory blood studies, liver and kidney tests
recommended.
Second medical opinion recommended before starting.
POSSIBLE INTERACTION WITH OTHER DRUGS
Generic Name or Drug Class Combined Effect
Flecainide Possible decreased
blood-cell production in
bone marrow.
Penicillins Decreased penicillin
effect.
Phenytoin Increased phenytoin
effect.
Tocainide Possible decreased
blood-cell production in
bone marrow.
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
Interacts With Combined Effect
Alcohol Possible liver problems.
May cause disulfiram
reaction (see Glossary).
What to do:
Overdose unlikely to threaten life. If person takes
much larger amount than prescribed, call doctor,
poison-control center or hospital emergency room for
instructions.
WARNINGS AND PRECAUTIONS
Don't take if:
You are allergic to any erythromycin.
You have had liver disease or impaired liver function.
Before you start, consult your doctor:
If you have taken erythromycin estolate in the past.
Over age 60:
Adverse reactions and side effects may be more frequent
and severe than in younger persons, especially skin
reactions around genitals and anus.
Pregnancy:
No proven harm to unborn child. Avoid if possible.
Breast-feeding:
Drug passes into milk. Avoid drug or discontinue
nursing until you finish medicine. Consult doctor for
advice on maintaining milk supply.
Infants and children:
Use only medical supervision.
Prolonged use:
You may become more susceptible to infections caused by
germs not responsive to erythromycin.
Skin and sunlight:
No problems expected.
Driving, piloting, or hazardous work:
No problems expected.
Discontinuing:
You must take full dose at least 10 consecutive days for
streptococcal or staphylococcal infections.
Others:
No problems expected.
POSSIBLE INTERACTION WITH OTHER DRUGS
Generic Name or Drug Class Combined Effect
Aminophylline Increased effect of
aminophylline in blood.
Lincomycins Decreased lincomycin
effect.
Oxtriphylline Increased level of
oxtriphylline in blood.
Penicillins Decreased penicillin
effect.
Theophylline Increased level of
theophylline in blood.
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
Interacts With Combined Effect
Alcohol Possible liver damage.
Beverages None expected.
Cocaine None expected.
Foods None expected.
Marijuana None expected.
Tobacco None expected.
CLINDAMYCIN
BRAND NAMES
Cleocin Dalacin C
Cleocin-T
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? No
Drug class: Antibiotic (lincomycin)
USES
Treatment of bacterial infections that are susceptible to
clindamycin.
DOSAGE AND USAGE INFORMATION
How to take:
Capsule or liquid--Swallow with liquid 1 hour before or
2 hours after eating.
When to take:
At the same time each day.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If
more than 2 hours, wait for next scheduled dose (don't
double this dose).
What drug does:
Destroys susceptible bacteria. Does not kill viruses.
Time lapse before drug works:
3 to 5 days.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
Symptoms What to Do
Life-threatening:
None expected.
Common:
None expected.
Infrequent:
Unusual thirst; Discontinue. Call doctor
vomiting; stomach right away.
cramps; severe and
watery diarrhea with
blood or mucus;
painful, swollen
joints; jaundice;
fever; tiredness;
weakness; weight loss.
White patches in Continue. Call doctor
mouth; rash, itch when convenient.
around groin, rectum
or armpits; vaginal
discharg, itching.
Rare:
None expected.
OVERDOSE
Symptoms:
Severe nausea, vomiting, diarrhea.
What to do:
Overdose unlikely to threaten life. If person takes
much larger amount than prescribed, call doctor,
poison-control center or hospital emergency room for
instructions.
WARNINGS AND PRECAUTIONS
Don't take if:
You are allergic to lincomycins.
You have had ulcerative colitis.
Prescribed for infant under 1 month old.
Before you start, consult your doctor:
If you have had yeast infections of mouth, skin or
vagina.
If you will have surgery within 2 months, including
dental surgery, requiring general or spinal anesthesia.
If you have kidney or liver disease.
If you have allergies of any kind.
Over age 60:
Adverse reactions and side effects may be more frequent
and severe than in younger persons.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't
use.
Breast-feeding:
Drug passes into milk. Avoid drug or discontinue
nursing until you finish medicine. Consult doctor for
advice on maintaining milk supply.
Infants and children:
Don't give to infants younger than 1 month. Use for
children only under medical supervision.
Prolonged use:
Severe colitis with diarrhea and bleeding.
You may become more susceptible to infections caused by
germs not responsive to clindamycin.
Skin and sunlight:
No problems expected.
Driving, piloting or hazardous work:
No problems expected.
Discontinuing:
Don't discontinue without doctor's advice until you
complete prescribed dose, even though symptoms diminish
or disappear.
POSSIBLE INTERACTION WITH OTHER DRUGS
Generic Name or Drug Class Combined Effect
Antidiarrheal Decreased clindamycin
preparations effect.
Chloramphenicol Decreased clindamycin
effect.
Erythromycin Decreased clindamycin
effect.
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
Interacts With Combined Effect
Alcohol None expected.
Beverages None expected.
Cocaine None expected.
Foods None expected.
Marijuana None expected.
Tobacco None expected.
LINCOMYCIN
BRAND AND GENERIC NAMES (Generic names in capitals)
Cleocin Lincocin
CLINDAYCIN LINCOMYCIN
Dalacin C
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? No
Drug class: Antibiotic (lincomycin)
USES
Treatment of bacterial infections that are susceptible to
lincomycin.
DOSAGE AND USAGE INFORMATION
How to take:
Capsule or liquid--Swallow with liquid 2 hour before or
2 hours afte reating.
When to take:
At the same times each day.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If
more than 2 hours, wait for next scheduled dose (don't
double this dose).
What drug does:
Time lapse before drug works:
3 to 5 days.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
Symptoms What To Do
Life-threatening:
None expected
Common:
None expected
Infrequent:
Unusual thirst; Discontinue. Call doctor
vomiting; stomach right away.
cramps; severe and
watery diarrhea with
blood or mucus; painful,
swollen joints; jaundice;
fever; tiredness;
weakness; weight loss;
rash; itch around groin,
rectum or armpits; white
patches in mouth; vaginal
discharge, itching.
Rare:
None expected.
OVERDOSE
Symptoms:
Severe nausea, vomiting, diarrhea.
What to do:
Overdose unlikely to threaten life. If person takes
much larger amount than prescribed, call doctor,
poison-control center or hospital emergency room for
instructions.
WARNINGS AND PRECAUTIONS
Don'take if:
You are allergic to lincomycins.
You have had ulcerative colitis.
Prescribed for infant under 1 month old.
Before you start, consult your doctor:
If you have had yeast infections of mouth, skin or
vagina.
If you will have surgery within 2 months, including
dental surgery, requiring general or spinal anesthesia.
If you have kidney or liver disease.
If you have allergies of any kind.
Over age 60:
Adverse reactions and side effects may be more frequent
and severe than in younger persons.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't
use.
Breast-feeding:
Drug passes into milk. Avoid drug or discontinue
nursing until you finish medicine. Consult doctor for
advice on maintaining milk supply.
Infants and children:
Don't give to infants younger than 1 month. Use for
children only under medical supervision.
Prolonged use:
Severe colitis with diarrhea and bleeding.
You may become more susceptible to infections caused by
germs not responsive to lincomycin.
Skin and sunlight:
No problems expected.
Driving, piloting or hazardous work:
No problems expected.
Discontinuing:
Don't discontinue without doctor's advice until you
complete prescribed dose, even though symptoms diminish
or disappear.
Others:
No problems expected.
POSSIBLE INTERACTION WITH OTHER DRUGS
Generic Name or Drug Class Combined Effect
Antidiarrheal Decreased lincomycin
preparations effect.
Chloramphenicol Decreased lincomycin
effect.
Erythromycin Decreased lincomycin
effect.
Loperamide May delay removal of
toxins from colon in
cases of diarrhea
caused by side effects
of lincomycin.
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
Interacts With Combined Effect
Alcohol None expected.
Infrequent:
Diarrhea, nausea, Discontinue. Call doctor
vomiting, abdominal right away.
pain.
Headache. Continue. Call doctor
when convenient.
Rare:
Blue fingernails, Discontinue. Seek emergency
lips and skin; treatment.
difficult breathing.
Sore throat, fever. Discontinue. Call doctor
right away.
OVERDOSE
Symptoms:
Nausea, vomiting, diarrhea.
What to do:
Overdose unlikely to threaten life. If person takes
much larger amount than prescribed, call doctor,
poison-control center or hospital emergency room for
instructions.
WARNINGS AND PRECAUTIONS
Don't take if:
You are allergic to trimethoprim or any sulfa drug.
Before you start, consult your doctor:
If you have had liver or kidney disease.
Over age 60:
Reduced liver and kidney function may require reduced
dose.
More likely to have severe anal and genital itch.
Increased susceptibility to anemia.
Pregnancy:
Studies inconclusive on harm to unborn child. Animal
studies show fetal abnormalities. Decide with your
doctor whether drug benefits justify risk to unborn
child.
Breast-feeding:
No proven harm to unborn child. Avoid if possible.
Infants and children:
Use under medical supervision only.
Prolonged use:
Anemia.
Skin and sunlight:
May cause rash or intensify sunburn in areas exposed to
sun or sunlamp.
Driving, piloting or hazardous work:
No problems expected.
Discontinuing:
Don't discontinue without doctor's advice until you
complete prescribed dose, even though symptoms diminish
or disappear.
Others:
No problems expected.
POSSIBLE INTERACTION WITH OTHER DRUGS
Generic Name or Drug Class Combined Effect
Diuretics (thiazide) Unusual bleeding or
bruising.
Flecainide Possible decreased
blood-cell production
in bone marrow.
Sulfamethoxazole Beneficial increase of
sulfamethoxazole effect.
Tocainide Possible decreased
blood-cell production
in bone marrow.
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
Interacts With Combined Effect
Alcohol Increased alcohol effect
with Bactrim or Septra.
Beverages None expected.
Cocaine No proven problems.
Foods None expected.
Marijuana None expected.
Tobacco None expected.
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