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SSRI INDUCED ALCOHOLISM, VIOLENCE AND BEHAVIOURS WITHIN THE CRIM
INAL JUSTICE SYSTEM
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Return to: Research Papers Alcohol
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#Post#: 13--------------------------------------------------
Mirtazapine improves alcohol detoxification
By: zebb Date: July 22, 2017, 4:59 pm
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https://www.ncbi.nlm.nih.gov/pubmed/15107190
J Psychopharmacol. 2004 Mar;18(1):88-93.
Mirtazapine improves alcohol detoxification.
Liappas J1, Paparrigopoulos T, Malitas P, Tzavellas E,
Christodoulou G.
Author information
Abstract
The objective of the present study was to determine whether a
combined psychotherapeutic-psychopharmacological (with
mirtazapine) treatment of collateral anxiety and depressive
symptomatology during the post-withdrawal phase of alcoholism
facilitates the process of alcohol detoxification, which is a
decisive stage in the treatment of alcohol-dependent
individuals. For that purpose, the rate of remission of anxiety
and depressive symptoms over a 4-week detoxification period was
evaluated between two groups: the first group followed a
standard detoxification protocol (n = 33) and the second group
was assigned to mirtazapine in addition to standard treatment
(n= 35). A marked reduction of anxiety and depressive symptoms
was demonstrated in both groups. However, patients on
mirtazapine improved more and at a faster rate compared to
controls. Thus, mirtazapine, used adjunctively to short-term
psychotherapy, may help the detoxification process by minimizing
physical and subjective discomfort. Consequently, it may improve
patient compliance in alcohol detoxification programs and
facilitate the initial phase treatment of alcohol abuse
dependence.
PMID: 15107190 DOI: 10.1177/0269881104040241
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