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#Post#: 27-------------------------------------------------- |
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how long does the protection last |
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By: gsgs Date: January 31, 2020, 12:38 pm |
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Little is known about the memory B-cell responses against |
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MERS-CoV, apart from a recent study which demonstrated the |
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persistence of anti-MERS-CoV antibodies in MERS survivors up to |
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34 months (Payne et al., 2016). On the other hand, antibody |
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responses against another closely related coronavirus, SARS-CoV, |
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were not persistent, whereby a 6-year follow-up study did not |
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detect memory B-cell responses in SARS survivors (Tang et al., |
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2011). It is likely that some of the B-cells differentiate into |
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MERS-CoV-specific memory B-cells following infection or |
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vaccination, but the longevity and protective efficacy of these |
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memory B-cells against MERS-CoV infection or re-challenge remain |
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unresolved questions (Du et al., 2016b; Perlman and Vijay, |
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2016). |
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688523/ |
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