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MS Speaks
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Return to: THE PRACTICAL SIDE OF BEING MULTIPLY SCLEROSED
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#Post#: 4849--------------------------------------------------
Thiazide diuretics
By: agate Date: June 28, 2025, 1:37 am
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MS sometimes involves "gravitational edema," or so I was told
long ago when I ran across a photo of someone with it who looked
a bit like me and I asked the neuro about it. Fluid collects and
you swell up.
Over many years I've been taking a thiazide diuretic to remedy
this problem. I get fewer vision problems and better mobility
from taking it, spread out in small doses over 24 hours.
Amazingly too it seems to help to prevent kidney stones.
For some time now I've been getting along on a reduced dosage of
it--from 100 mg/day to 50mg/day, and once again now I'm reducing
the dosage, down to 37.5mg/day. I'm taking that in the form of
12.5 mg 3 times in 24 hours, spread out at intervals of
approximately 8 hours.
If I swell up too much or have even the slightest sign of kidney
stone pain, I'm apt to resume the old dosage.
Kidney stone pain is one of the worst kinds of pain I've ever
had.
I'm not recommending this medicine (hydrochlorothiazide is the
one I'm on now but there are others that have similar effects)
to anyone with MS. But it has helped me.
#Post#: 4875--------------------------------------------------
Re: Thiazide diuretics--update
By: agate Date: July 22, 2025, 12:56 am
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It's been almost a month now since I reduced the HCTZ dosage by
12.5mg. So far, so good.
In fact, I feel somewhat stronger. Or maybe it is just that
there haven't been any major spells of hot weather lately.
I did have a couple of abnormal lab test results that were
significant enough for the doctor to propose a drug to help with
proteinuria.
I had proteinuria only just before being diagnosed with Type 2
diabetes, many years ago. The tests have been normal ever
since--and so this abnormal test result is surprising. It might
or might not have some connection with the change in the HCTZ
dosage.
I haven't yet learned what drug is being considered but have let
the doctor know that I'd like to wait a while and see if I can
have a normal test result after a while.
I'm of the opinion--and some experts are of the same
opinion--that people my age should probably be very cautious
about starting any new drug.
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