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Return to: TECFIDERA (dimethyl fumarate, BG-12, Fumaderm) |
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#Post#: 4220-------------------------------------------------- |
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(Abst.) Discontinuation of dimethyl fumarate in MS --a nationwid |
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e study [Denmark] |
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By: agate Date: November 15, 2023, 1:45 am |
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From PubMed (November 14, 2023)--"Discontinuation of dimethyl |
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fumarate in multiple sclerosis--a nationwide study": |
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https://pubmed.ncbi.nlm.nih.gov/37956521/ |
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The authors conclude that |
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[quote]In this population-based study, we found major |
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differences between the MS clinics in rates and reason for |
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discontinuation of DMF. Our results suggest that management |
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strategies during DMF treatment can reduce discontinuation |
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rates.[/quote] |
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Of the experimental subjects, 54.5% stopped taking Tecfidera |
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because of adverse events, and 26.1% stopped taking it because |
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of "active disease." It looks as if Tecfidera hasn't gone over |
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very well, all in all. And the solution to this, the authors |
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suggest, might be better "management strategies." |
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The MS clinics are probably being told, in effect, that they |
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need to manage their patients on Tecfidera better. I wonder what |
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this means though. |
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When I've been taking an MS drug (Avonex, Copaxone, Glatopa), |
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the prescribing neurologist just prescribed it and ordered some |
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standard lab work and had very little to say otherwise on the |
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topic. When I wanted to stop the Avonex and later the Copaxone, |
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there was no attempt at persuading me to continue. Would these |
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better management strategies mean that patients wanting to stop |
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an MS drug (like Tecifidera) will be more actively encouraged to |
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stay on it? |
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