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Return to: Central Nervous system and Tissue Engineering |
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#Post#: 46-------------------------------------------------- |
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Neural tissue engineering of the CNS using hydrogels |
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By: fmsbi Date: December 25, 2014, 6:43 pm |
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Nisbet, D.R.ab, Crompton, K.E.ab, Horne, M.K.c, Finkelstein, |
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D.I.d, Forsythe, J.S.ab |
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a Department of Materials Engineering, Division of Biological |
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Engineering, Monash University, Wellington Road, Clayton, VIC |
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3800, Australia |
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b CRC for Polymers, 8 Redwood Drive, Notting Hill, VIC 3168, |
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Australia |
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c Howard Florey Institute, University of Melbourne, VIC 3010, |
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Australia |
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d Mental Health Research Institute of Victoria, 155 Oak Street, |
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Locked Bag 11, Parkville, VIC 3052, Australia |
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Abstract |
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Current therapies have limited capacity to curtail disease |
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progression or damage of the central nervous system (CNS) of |
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adult mammals and successful regeneration following injury or |
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disease does not occur. Regeneration of the CNS is limited by |
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physical and chemical inhibitory barriers within the injured |
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environment and the absence of positive cues that elicit and |
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guide repair. Neural tissue engineering strategies focus on |
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developing scaffolds that artificially generate favourable |
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cellular microenvironments that attempt to tip the balance in |
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favour of regeneration. Some recent advances using scaffolds to |
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promote regeneration within the CNS, particularly in conjunction |
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with stem cells, has generated promising results. This review |
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focuses on hydrogel scaffolds which have been used extensively |
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in neural tissue engineering applications and addresses the |
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physical and chemical modifications of these materials to |
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promote nerve regeneration. � 2007 Wiley Periodicals, Inc. |
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#Post#: 49-------------------------------------------------- |
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Re: Neural tissue engineering of the CNS using hydrogels |
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By: SSamani Date: December 26, 2014, 12:47 am |
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Hi |
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Download full paper. |
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Thanks |
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[center]Download link |
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http://www.uplooder.net/cgi-bin/dl.cgi?key=a1a62bbcd77d4aa95c1485c647b5e4e7[/ce… |
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