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Return to: Liver Tissue Engineering |
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#Post#: 40-------------------------------------------------- |
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HEPATIC TISSUE ENGINEERING |
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By: fmsbi Date: December 25, 2014, 6:15 pm |
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Liver tissue engineering aims to provide novel therapies for |
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liver diseases and to create |
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effective tools for understanding fundamental aspects of liver |
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biology and pathologic processes. |
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Approaches range from bio-mimetic in vitro model systems of the |
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liver to three-dimensional |
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implantable constructs. Collectively, these cell-based |
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approaches endeavor to replace or enhance |
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organ transplantation, which is the current standard treatment |
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for liver diseases in most clinical |
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settings. However, the complexity of liver structure and |
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function as well as the limited supply of |
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human hepatocytes pose unique challenges for the field. This |
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chapter reviews advances in the |
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field of liver tissue engineering within the context of current |
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therapies for liver diseases and |
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clinical alternatives such as cell transplantation strategies |
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and extracorporeal bioartificial liver |
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devices. |
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http://lmrt.mit.edu/books/2011/hepatic_2011.pdf |
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http://lmrt.mit.edu/books/2011/hepatic_2011.pdf |
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