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Subject: rec.pets.dogs:  PennHip FAQ
Summary: Article discussing the PennHip method of orthopedic evaluation
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Last-modified: 13 May 1997

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                              PennHIP FAQ Sheet

    _________________________________________________________________

                                                               ICG 03/95

                   Questions and Answers about PennHIP
   A New Scientific Method for Early Screening for Canine Hip Dysplasia

    * Introduction
    * What Exactly Is PennHIP?
    * How Was PennHIP Developed?
    * How Does PennHIP Differ from Evaluation Methods Which Use the Hip
      Extended Position?
    * What Happens to My Dog During a PennHIP Evaluation?
    * What Is the Cost of Having My Dog Evaluated?
    * Is PennHIP Going To Replace Other Commercially Available Systems?
    * Will AKC and Other Breed Registration Organizations "Recognize"
      PennHIP?
    * Are the Results Confidential?
    * How Does This Benefit Me as an Owner or Breeder of Dogs?
    * How Can I Get the Name of a PennHIP Veterinarian or Get Answers to
      Additional Questions?


    _________________________________________________________________

   Introduction

  Canine Hip Dysplasia (CHD) is the most common, heritable orthopedic
  problem seen in dogs. It affects virtually all breeds of dogs but is
  especially problematic in large and giant breeds. Clinically, the
  disease manifests itself in one of two ways:

   1. a severe form that typically afflicts the younger animal and is
      usually characterized by marked pain and lameness, or
   2. a more chronic form with more gradual onset of clinical signs such
      as mild intermittent pain, stiffness and restricted range of
      motion in the hips as the dog ages. In many cases, the chronic
      form may be clinically silent.

  Breeders and veterinarians have long sought a reliable method to
  determine the likelihood of a dog developing CHD and passing that
  genetic trait to any offspring. It was generally recognized that the
  current diagnostic methods of hip evaluation were associated with
  disappointing progress in reducing the frequency of CHD. In 1983, Dr.
  Gail Smith, a veterinary orthopedic surgeon and bioengineer from the
  University of Pennsylvania School of Veterinary Medicine, began to
  actively research and develop a new scientific method for the early
  diagnosis of Canine Hip Dysplasia. Research in his laboratory resulted
  in a diagnostic method capable of estimating the susceptibility for
  CHD in populations of dogs as young as sixteen weeks. The method has
  shown distinct advantages over the standard CHD diagnostic method that
  evaluates dogs at two years or older. The university of Pennsylvania
  Hip Improvement Program (PennHIP) was founded as an extension of Dr.
  Smith's laboratory research. Below are answers to some commonly asked
  questions about the PennHIP method.

   What Exactly Is PennHIP?

  PennHIP is a scientific method to evaluate a dog for its
  susceptibility to develop Hip Dysplasia. The radiographic procedure
  involves a special positioning of the dog so that the dog's "passive
  hip laxity" can be accurately measured. In simple terms, passive hip
  laxity refers to the degree of looseness of the hip ball in the hip
  socket when the dog's muscles are completely relaxed. Research has
  shown that the degree of passive hip laxity is an important factor in
  determining susceptibility to develop Degenerative Joint Disease (DJD)
  later in life. Radiographic evidence of hip DJD, also known as
  osteoarthritis, is the universally accepted confirmation of CHD.
  PennHIP is being marketed by International Canine Genetics, Inc. (ICG)
  of Malvern, PA.

   How Was PennHIP developed?

  The development of PennHIP has involved multiple disciplines including
  biomechanics, orthopedics, clinical medicine, radiology, epidemiology
  and population genetics. The first phase of development involved
  sophisticated biomechanical testing to determine the optimal patient
  position for measuring hip laxity. By monitoring passive hip laxity in
  dogs as they matured, it was discovered that hip laxity was the
  primary factor in the development of the DJD characteristic of CHD.
  That is, the radiographic expression of DJD was statistically
  significantly correlated with the degree of measured passive hip
  laxity. In addition, the CHD prediction was shown to be acceptably
  accurate in populations of puppies as young as sixteen weeks of age.
  Moreover, the correlation between passive hip laxity and subsequent
  hip DJD was shown to increase over the four-month figures when hips
  were evaluated at six months and twelve months of age. In the same
  studies, it was shown that there was no statistically significant
  correlation between laxity and DJD when the standard hip extended
  position was used. In addition, no other method used to evaluate for
  CHD has undergone similar rigorous testing through controlled
  scientific studies to determine diagnostic accuracy.

   How Does PennHIP Differ from Evaluation Methods Which Use the Hip Extended
   Position?

  PennHIP differs in some very fundamental and important ways. First,
  PennHIP was developed and tested following strict scientific protocol
  and the results of these studies have been published (and continue to
  be) in peer-reviewed, scientific journals. More than a decade of
  research and analysis has produced a body of information in support of
  PennHIP's effectiveness. As with all diagnostic tests, PennHIP's
  accuracy is not 100 percent, but in direct comparisons it is far
  superior to any other available diagnostic method. Second, passive hip
  laxity is objectively measured and the resulting Hip Evaluation Report
  is not issued in a pass/fail framework. PennHIP specifically measures
  passive joint laxity and includes the quantitative measurement in its
  report. Based on the degree of laxity, the individual dog is then
  ranked relative to other members of the same breed. (Note: Breed
  specific rankings are given when there are twenty or more evaluations.
  If there are fewer than twenty evaluations - ranking is made to the
  general dog population.) For Example, a dog receiving a ranking in the
  70th percentile means that thirty percent of its breed members have
  hips that are tighter. This allows breeders to easily identify those
  animals with tighter hips within each breed. As shown in our studies,
  dogs with tighter hips are less likely to develop CHD and pass that
  genetic tendency on to future generations. Third, because PennHIP is
  measuring maximal passive hip laxity, the position of the patient is
  very different from the hip-extended position. The hip-extended
  position has been used for more than thirty years to screen hips for
  either DJD, laxity or both. Laboratory studies, however, have
  indicated wide diagnostic variability among radiologists in
  interpreting this view. Further, through biomechanical testing, the
  hip-extended view was found to mask the underlying true joint laxity
  and through direct comparison, the predictive value for CHD was shown
  to be inferior to the PennHIP procedure. Most importantly, the
  heritability of the diseased phenotype scored in the hip-extended view
  has not been studied in most breeds of dogs. A knowledge of
  heritability is critical to determine whether the selection pressure
  will produce genetic change. Estimates for the heritability of passive
  hip laxity drawn from analysis of full pedigrees for the breeds
  examined thus far in the studies show high values (for German Shepherd
  Dogs, heritability = 0.61). Fourth, the PennHIP method is based on
  strict quality control. To take PennHIP radiographs, veterinarians
  must undergo training and a certification process to demonstrate
  competency. The data generated from PennHIP undergoes regular review
  and statistical analysis so that useful information, by breed, is
  available to judge progress toward reducing CHD. For optimal validity,
  it is mandatory that all PennHIP radiographs be submitted for analysis
  and inclusion in the PennHIP database. This policy eliminates the
  practice of prescreening radiographs and sending only the best for
  evaluation, resulting in biased hip data for any given breed.

   What Happens to My Dog During a PennHIP Evaluation?

  To obtain diagnostic radiographs, it is important that the patient and
  the surrounding hip musculature be completely relaxed. For the comfort
  and safety of the animal, this required sedation, however some
  veterinarians prefer general anesthesia. Typically, three separate
  radiographs are made during an evaluation. The first is a compression
  view where the femurs are positioned in a neutral, stance-phase
  orientation and the femoral heads are pushed fully into the sockets.
  This helps show the true depth of the hip socket and gives an
  indication of the "fit" of the ball in the socket. The second
  radiograph is the distraction view. Again, the hips are positioned in
  a neutral orientation and a special positioning device is used to
  apply a harmless force to cause the hips to displace laterally. This
  position is the most accurate and sensitive for showing the degree of
  passive laxity. Passive laxity has been shown to correlate with the
  susceptibility to develop DJD. A hip extended view is also included
  for the sole purpose of examining for any existing joint disease such
  as osteoarthritis. The PennHIP procedure has been safely performed on
  thousands of patients.

   What Is the Cost of Having My Dog Evaluated?

  The total fee for a PennHIP evaluation is determined by the
  veterinarian providing the service. It is important to remember that
  the total service includes sedation/anesthesia, three radiographs,
  office consultation and all charges associated with mailing and film
  evaluation. You will not find it necessary to write a separate check
  for evaluation fees or mail your dog's films. The veterinarian
  performing the procedure is responsible for payment and film
  submission. The film evaluation charge (currently $25.00) will be
  included in the total cost of a PennHIP evaluation.

   Is PennHIP Going To Replace Other Commercially Available Systems?

  As technology advances, the veterinary professional community will
  offer and utilize improved methods of disease diagnosis. The dog
  breeding community will also endorse those methods that help them
  achieve their goals of reducing the frequency of hip Dysplasia in dogs
  while maintaining other desirable traits and features. The PennHIP
  technology and research have been and will continue to be, fully
  presented to the veterinary medical community for its review. PennHIP
  has been received enthusiastically as a major step toward reducing the
  frequency of CHD. We encourage and welcome continued scientific
  examination and comparison of PennHIP to any available or new methods
  of canine hip Dysplasia diagnosis.

   Will AKC and Other Breed Registration Organizations "Recognize" PennHIP?

  ICG is working with many organizations to present the PennHIP
  technology and the positive impact it holds for reducing Canine Hip
  Dysplasia. It is conceivable that at some point a PennHIP reference
  might be included as part of the dog's registry information. However,
  all hip evaluation reports are considered confidential medical
  information and are released only to the PennHIP veterinarian and the
  owner of the dog (unless the owner requests otherwise).

   How Does This Benefit Me as an Owner or Breeder of Dogs?

  Scientific data confirms that the PennHIP method surpasses other
  diagnostic methods in the ability to accurately predict susceptibility
  to developing CHD. The method can be performed on dogs as young as
  sixteen weeks of age compared with two years using the standard
  technique. The ability to receive an early estimate of a dog's hip
  integrity is important whether the dog's intended purpose will be for
  breeding, for working or as a family pet. The data generated by
  PennHIP will allow breeders to confidently identify the members of
  their breeding stock with the tightest hips. The PennHIP
  interpretation will also permit breeders to assess the progress they
  are making with their breeding program as they strive to reduce the
  amount of hip laxity in their dogs. Pet owners are able to assess
  their pet's risk of developing CHD, and make lifestyle adjustments for
  their dog, if necessary, to enhance the quality of their pet's life.

   How Can I Get the Name of a PennHIP Veterinarian or Get Answers to
   Additional Questions?

  To obtain the name of a veterinarian near you who is trained and
  certified to perform the PennHIP procedure, call ICG at
  1-800-248-8099. If there is not a veterinarian near you presently,
  additional veterinarians are being trained throughout the country. If
  your veterinarian would like to learn more about PennHIP, please have
  him/her contact ICG directly.

    _________________________________________________________________

                           For more information
                           Call 1-800-248-8099
         or inquire via email to ICG at [email protected]
                                 [INLINE]
                      International Canine Genetics
               271 Great Valley Parkway, Malvern, PA 19355

    _________________________________________________________________


   PennHip FAQ
   Internet Version kept by Bill Faulk, [email protected]