\documentclass{standalone}
\usepackage{luamplib}
\begin{document}
\mplibtextextlabel{enable}
\begin{mplibcode}
input colorbrewer-rgb
ahangle := 30;
beginfig(1);
 numeric u;
 u = 42;
 path xx, yy, f;
 xx = (1/4 left -- 17/4 right) scaled u;
 yy = (1/4 down -- 9/4 up) scaled u;

 f = ((15/32,32/15) for x = 1/2 step 1/8 until 33/8: .. (x,1/x) endfor) scaled u;

 path A; A = % keep next on it's own line....
 buildcycle(yy shifted (u,0), f, yy shifted (2.71828u,0), xx)
 ;
 fill A withcolor Blues 8 2;

 drawoptions(withcolor 3/4);
 for x=1 upto 4:
   draw yy shifted (x*u,0) cutafter (xx shifted (0, ypart point 0 of f));
 endfor
 for y=1 upto 2:
   draw xx shifted (0,y*u) cutafter (yy shifted (xpart point infinity of f,0));
 endfor

 drawoptions();
 draw f withcolor Reds 8 7;
 drawarrow xx;
 drawarrow yy;

endfig;
\end{mplibcode}
\end{document}