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on Gopher (inofficial) |
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Visit Hacker News on the Web |
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COMMENT PAGE FOR: |
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Efficient mRNA delivery to resting T cells to reverse HIV latency |
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sroussey wrote 3 hours 50 min ago: |
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I wonder if this can be used for other latent viruses that embed in |
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cells like herpes and chickenpox/shingles. |
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stephen_g wrote 47 min ago: |
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Yeah, latent EBV would be great too since it seems to be one of the |
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main causes of MS. |
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I believe this is already being researched with mRNA now, it would be |
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amazing if it works out and we could treat all of these. |
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XorNot wrote 2 hours 8 min ago: |
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That would be interesting because both of those have links to various |
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late-life neurological conditions aa well. |
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Zigurd wrote 6 hours 22 min ago: |
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MRNA therapies have such high potential, there really ought to be much |
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more public education and outreach to prevent people falling down the |
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quackery rabbit hole. I don't just say that to pile on to the quacks. |
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It's so detrimental and costs so many lives that it's probably a target |
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for influence by adversary nation actors. |
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dpe82 wrote 2 hours 19 min ago: |
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If we hadn't had a pandemic in which lots of people lost their |
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collective minds and an irresponsible political machine that took |
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advantage of that, mRNA would be pretty universally hailed as the |
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miracle it is. |
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That aside, yes. Education is important. Sadly at least in the US |
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some of the people who lost their minds are now in charge of such |
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education. |
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chasil wrote 2 hours 13 min ago: |
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This article asserts that white blood cells are the target, but we |
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also know that (within the brain) astrocytes and [iirc] microglia |
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can bear latent infection. |
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Is such a carrier capable of addressing latent reservoirs inside |
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the blood-brain barrier? Can it cross the barrier, pervade the |
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cerebrospinal fluid, then penetrate all infected cells? |
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White blood cells are a fantastic achievement, but far from the |
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whole story. |
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the_real_cher wrote 2 hours 32 min ago: |
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Lobotomy's were viewed to have so much high potential back in the day |
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that they won the Nobel prize. |
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In true scientific fashion both sides would ideally just stick with |
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the facts. |
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hobs wrote 26 min ago: |
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There's no "both sides" in science. |
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Jalad wrote 6 hours 52 min ago: |
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Also discussed here |
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[1]: https://news.ycombinator.com/item?id=44202664 |
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